Factors Affecting Drug Metabolism

Factors affecting drug metabolism Drug metabolism is the metabolic breakdown of drugs, through specialised enzymatic systems. Liver is the principal site of drug metabolism, additional sites are kidney, gut, lungs and plasma. Once the drug shows its pharmacological action, the remaining amount of drug should be excreted from body. Metabolism plays an important role in … Read more

Drug Metabolism Principles- Phase I and Phase II Reactions

Introduction The drug is eliminated irreversibly from the body by two processes, one is metabolism and other is excretion. The process of biotransformation of drugs or non-essential foreign chemicals in the body, to remove out of the body this process is referred as drug metabolism. Unabsorbed drug or non-essential chemical is made hydrophilic to remove … Read more