Pharmacy Practice MCQ, in this article we will solve, Practice MCQ on the topic, Solubility expressions and mechanism of solute solvent interactions. Read following article for your reference.
Solubility Expressions And Mechanism Of Solute Solvent Interactions » PHARMACAREERS
- What is solubility?
- A. The ability of a solute to dissolve in a solvent
- B. The ability of a solvent to dissolve in a solute
- C. The ability of a substance to evaporate
- D. The ability of a substance to condense
- Which of the following is NOT a solubility expression?
- A. Molarity
- B. Molality
- C. Percentage by mass
- D. Density
- What does molality measure?
- A. Moles of solute per liter of solution
- B. Moles of solute per kilogram of solvent
- C. Grams of solute per liter of solution
- D. Grams of solute per kilogram of solvent
- Which solubility expression is temperature-independent?
- A. Molarity
- B. Molality
- C. Percentage by volume
- D. Percentage by mass
- What is the solubility expression used by the United States Pharmacopeia (USP)?
- A. Molarity
- B. Molality
- C. Amount of solvent per unit of solute
- D. Percentage by mass
- What is the first step in the solute-solvent interaction mechanism?
- A. Creation of a cavity in the solvent
- B. Insertion of the solute into the solvent
- C. Removal of the solute molecule from its crystal
- D. Formation of hydrogen bonds
- Which factor does NOT influence solubility?
- A. Temperature
- B. Pressure
- C. Color of the solute
- D. pH
- What type of solvent is water considered?
- A. Nonpolar solvent
- B. Polar solvent
- C. Semi-polar solvent
- D. Amphipathic solvent
- Which type of interaction is crucial for the solubility of ionic solutes in polar solvents?
- A. Van der Waals forces
- B. Hydrogen bonding
- C. Dipole-dipole interactions
- D. Covalent bonding
- What is the role of hydrogen bonds in solubility?
- A. They decrease solubility
- B. They increase solubility
- C. They have no effect on solubility
- D. They only affect nonpolar solutes
- How does temperature generally affect solubility?
- A. Increases solubility
- B. Decreases solubility
- C. Has no effect
- D. Depends on the solute
- What happens to solubility when pressure is increased?
- A. Solubility decreases
- B. Solubility increases
- C. Solubility remains the same
- D. Solubility fluctuates
- Which pH condition generally increases the solubility of acidic drugs?
- A. Acidic pH
- B. Neutral pH
- C. Basic pH
- D. pH has no effect
- What is the effect of particle size on solubility?
- A. Larger particles dissolve faster
- B. Smaller particles dissolve faster
- C. Particle size has no effect
- D. Only affects nonpolar solutes
- Which factor is NOT a physical property affecting solubility?
- A. Particle size
- B. Surface area
- C. Color
- D. Crystallographic factors
- What type of solvent is petroleum considered?
- A. Polar solvent
- B. Nonpolar solvent
- C. Semi-polar solvent
- D. Amphipathic solvent
- What is the principle of “like dissolves like”?
- A. Polar solvents dissolve nonpolar solutes
- B. Nonpolar solvents dissolve polar solutes
- C. Polar solvents dissolve polar solutes
- D. Nonpolar solvents dissolve ionic solutes
- Which of the following is a semi-polar solvent?
- A. Water
- B. Ethanol
- C. Hexane
- D. Benzene
- What is the significance of the dipole moment in solubility?
- A. It decreases solubility
- B. It increases solubility
- C. It has no effect on solubility
- D. It only affects nonpolar solutes
- Which interaction is more important than polarity for solubility?
- A. Van der Waals forces
- B. Hydrogen bonding
- C. Covalent bonding
- D. Ionic bonding
- What is the term for a solution that can dissolve more solute at a given temperature?
- A. Saturated solution
- B. Unsaturated solution
- C. Supersaturated solution
- D. Dilute solution
- What is the term for a solution that has dissolved the maximum amount of solute at a given temperature?
- A. Saturated solution
- B. Unsaturated solution
- C. Supersaturated solution
- D. Concentrated solution
- What is the term for a solution that contains more solute than it can theoretically hold at a given temperature?
- A. Saturated solution
- B. Unsaturated solution
- C. Supersaturated solution
- D. Dilute solution
- Which factor does NOT affect the dissolution rate of a solute?
- A. Temperature
- B. Stirring
- C. Particle size
- D. Color
- What is the effect of increasing the surface area of a solute on its dissolution rate?
- A. Decreases the dissolution rate
- B. Increases the dissolution rate
- C. Has no effect
- D. Only affects nonpolar solutes
- Which of the following is NOT a method to enhance solubility?
- A. Particle size reduction
- B. Use of surfactants
- C. Increasing the color intensity
- D. Complexation
- What is the role of surfactants in solubility?
- A. They decrease solubility
- B. They increase solubility
- C. They have no effect on solubility
- D. They only affect nonpolar solutes
- What is complexation in the context of solubility?
- A. Formation of a complex between solute and solvent
- B. Reduction of particle size
- C. Use of surfactants
- D. Increase in temperature
- Which of the following is a common solvent used in pharmaceutical formulations?
- A. Water
- B. Hexane
- C. Benzene
- D. Toluene
- What is the effect of pH on the solubility of basic drugs?
- A. Acidic pH increases solubility
- B. Basic pH increases solubility
- C. Neutral pH increases solubility
- D. pH has no effect
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