Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject physical pharmaceutics II. Read following article for your reference.
Micromeretics, Particle Size And Distribution, Mean Particle Size » PHARMACAREERS
- What is micromeretics?
- a) The study of large particles
- b) The science and technology of small particles
- c) The study of chemical reactions
- d) The science of measuring liquid viscosity
- What does particle size distribution refer to?
- a) The uniformity in particle size
- b) The variation in sizes of particles within a sample
- c) The shape of particles
- d) The color of particles
- Why is particle size distribution important in pharmaceuticals?
- a) It affects the taste of the medication
- b) It impacts the dissolution rate and bioavailability of drugs
- c) It changes the color of the medication
- d) It influences the smell of the medication
- Which instrument is commonly used to measure particle size distribution?
- a) Microscope
- b) Sieve analyzer
- c) Spectrophotometer
- d) Thermometer
- What is the mean particle size?
- a) The size of the smallest particle in a sample
- b) The average size of particles in a sample
- c) The size of the largest particle in a sample
- d) The uniform size of all particles in a sample
- Which method is NOT used for particle size analysis?
- a) Laser diffraction
- b) Sedimentation
- c) Dynamic light scattering
- d) Colorimetry
- What does a narrow particle size distribution indicate?
- a) Large variation in particle sizes
- b) Uniform particle sizes
- c) Irregular particle shapes
- d) High particle porosity
- Why is controlling particle size important in tablet formulation?
- a) To ensure uniform color
- b) To maintain consistent drug release rates
- c) To improve the taste
- d) To enhance the odor
- What is the significance of surface area in micromeretics?
- a) It affects the dissolution rate and chemical reactivity
- b) It changes the color of particles
- c) It influences the taste of particles
- d) It determines the hardness of particles
- Which of the following techniques measures particle size by analyzing the scattering pattern of a laser beam?
- a) Sieve analysis
- b) Laser diffraction
- c) Microscopy
- d) Gas adsorption
- What is the primary factor affecting the flow properties of powders?
- a) Particle color
- b) Particle size and shape
- c) Particle density
- d) Particle temperature
- Which parameter is crucial for determining the sedimentation rate of particles in a suspension?
- a) Particle color
- b) Particle density and size
- c) Particle temperature
- d) Particle solubility
- What does a wide particle size distribution indicate?
- a) Uniform particle sizes
- b) Large variation in particle sizes
- c) Irregular particle shapes
- d) Low particle porosity
- What is the significance of the polydispersity index (PDI) in particle size analysis?
- a) It measures the average particle size
- b) It indicates the uniformity of particle sizes
- c) It measures particle color variation
- d) It indicates the chemical composition of particles
- Which technique is used to determine the size of particles suspended in a liquid medium by measuring their rate of sedimentation?
- a) Sieve analysis
- b) Sedimentation
- c) Laser diffraction
- d) Microscopy
- What is the advantage of using laser diffraction for particle size analysis?
- a) It provides high-resolution images
- b) It measures a wide range of particle sizes rapidly
- c) It changes the color of particles
- d) It enhances particle solubility
- Which property is critical for the compaction behavior of powders in tablet formulation?
- a) Particle shape
- b) Particle size distribution
- c) Particle color
- d) Particle odor
- What is the role of dynamic light scattering (DLS) in particle size analysis?
- a) To measure the dissolution rate of particles
- b) To determine the size distribution of small particles in a suspension
- c) To analyze particle color
- d) To measure the temperature of particles
- Why is particle shape an important parameter in micromeretics?
- a) It affects the color of particles
- b) It influences the flow and packing properties of powders
- c) It changes the taste of particles
- d) It alters the chemical composition of particles
- Which method uses a series of sieves with different mesh sizes to determine particle size distribution?
- a) Laser diffraction
- b) Sieve analysis
- c) Dynamic light scattering
- d) Microscopy
- How does particle size affect the dissolution rate of a drug?
- a) Smaller particles dissolve faster due to increased surface area
- b) Larger particles dissolve faster due to greater mass
- c) Particle size has no effect on dissolution rate
- d) Particle size only affects color, not dissolution
- What does the term ‘monodisperse’ mean in the context of particle size distribution?
- a) Particles have a wide range of sizes
- b) Particles are uniform in size
- c) Particles are irregularly shaped
- d) Particles have varying colors
- Which of the following factors can influence the particle size distribution in a sample?
- a) Milling process
- b) Drying method
- c) Agglomeration
- d) All of the above
- What is the relationship between particle size and surface area?
- a) Larger particles have greater surface area
- b) Smaller particles have greater surface area
- c) Particle size does not affect surface area
- d) Surface area is only influenced by particle color
- Why is the specific surface area an important parameter in micromeretics?
- a) It affects the color of particles
- b) It influences the chemical reactivity and dissolution rate of particles
- c) It changes the taste of particles
- d) It determines the density of particles
- Which method measures the particle size distribution by analyzing the pattern of light scattered by a suspension of particles?
- a) Sieve analysis
- b) Laser diffraction
- c) Microscopy
- d) Gas adsorption
- What is the effect of particle size on the flowability of powders?
- a) Smaller particles generally have better flowability
- b) Larger particles generally have better flowability
- c) Particle size does not affect flowability
- d) Flowability is only influenced by particle color
- What is the primary goal of particle size reduction in pharmaceutical processes?
- a) To enhance the solubility and dissolution rate of drugs
- b) To change the color of particles
- c) To increase the odor of particles
- d) To reduce the density of particles
- Which technique is used to visualize and measure the shape and size of individual particles?
- a) Microscopy
- b) Spectrophotometry
- c) Gas chromatography
- d) Colorimetry
- What is the significance of the term ‘mean particle size’ in a sample?
- a) It represents the smallest particle size in the sample
- b) It represents the largest particle size in the sample
- c) It represents the average size of particles in the sample
- d) It indicates the color variation in the sample
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