Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject physical pharmaceutics. Read following article for your reference. 

Critical Solution Temperature (CST) And Distribution Law » PHARMACAREERS

 

  1. What is the Critical Solution Temperature (CST)?
    • A) The temperature at which two immiscible liquids become partially miscible
    • B) The temperature at which two partially miscible liquids become completely miscible
    • C) The temperature at which a solid dissolves in a liquid
    • D) The temperature at which a gas dissolves in a liquid
  2. Which of the following is true about Upper Critical Solution Temperature (UCST)?
    • A) It is the lowest temperature at which phase separation occurs
    • B) It is the highest temperature at which phase separation occurs
    • C) It is the temperature at which a solid melts
    • D) It is the temperature at which a gas liquefies
  3. What does LCST stand for?
    • A) Lower Critical Solution Temperature
    • B) Lowest Critical Solution Temperature
    • C) Liquid Critical Solution Temperature
    • D) Limited Critical Solution Temperature
  4. At what point does the Gibbs free energy change for mixing become zero?
    • A) At the melting point
    • B) At the boiling point
    • C) At the Critical Solution Temperature
    • D) At the freezing point
  5. Which phase diagram shape is typically associated with UCST?
    • A) Dome-shaped curve
    • B) Linear curve
    • C) Exponential curve
    • D) Parabolic curve
  6. What is the primary factor affecting CST?
    • A) Pressure
    • B) Temperature
    • C) Volume
    • D) Concentration
  7. What does the distribution law state?
    • A) A solute will distribute itself between two immiscible solvents in a constant ratio at a given temperature
    • B) A solute will distribute itself between two miscible solvents in a constant ratio at a given temperature
    • C) A solute will distribute itself between two immiscible solvents in a variable ratio at a given temperature
    • D) A solute will distribute itself between two miscible solvents in a variable ratio at a given temperature
  8. Which of the following is NOT a type of CST?
    • A) UCST
    • B) LCST
    • C) MCST
    • D) None of the above
  9. What is the significance of CST in pharmaceutics?
    • A) Optimizing formulations
    • B) Ensuring drug solubility
    • C) Creating stable emulsions
    • D) All of the above
  10. What does a phase diagram plot?
    • A) Temperature against pressure
    • B) Temperature against composition
    • C) Pressure against volume
    • D) Volume against composition
  11. Which system is commonly used to study CST?
    • A) Water-oil system
    • B) Phenol-water system
    • C) Alcohol-water system
    • D) Ether-water system
  12. What happens to two liquids at the CST?
    • A) They become completely immiscible
    • B) They become completely miscible
    • C) They form a solid
    • D) They evaporate
  13. What is the role of enthalpy change (ΔH) in determining CST?
    • A) It has no role
    • B) It determines the pressure
    • C) It influences the temperature
    • D) It influences the volume
  14. What does the term ‘partially miscible’ mean?
    • A) Liquids that do not mix at all
    • B) Liquids that mix in all proportions
    • C) Liquids that mix in limited proportions
    • D) Liquids that form a solid
  15. Which of the following is a limitation of the distribution law?
    • A) It applies only to gases
    • B) It applies only to solids
    • C) It applies only to immiscible liquids
    • D) It applies only to miscible liquids
  16. What is the effect of temperature on the distribution ratio?
    • A) It remains constant
    • B) It decreases with temperature
    • C) It increases with temperature
    • D) It varies with temperature
  17. Which of the following is an application of the distribution law?
    • A) Drug absorption
    • B) Bioavailability
    • C) Formulation design
    • D) All of the above
  18. What does the term ‘miscible’ mean?
    • A) Capable of being mixed
    • B) Incapable of being mixed
    • C) Capable of being dissolved
    • D) Incapable of being dissolved
  19. What is the significance of phase diagrams in CST?
    • A) They show the regions of miscibility and immiscibility
    • B) They show the regions of solubility and insolubility
    • C) They show the regions of stability and instability
    • D) They show the regions of reactivity and non-reactivity
  20. What is the primary use of CST in drug formulation?
    • A) To determine the melting point
    • B) To optimize drug solubility
    • C) To measure drug potency
    • D) To assess drug stability
  21. Which of the following factors does NOT affect CST?
    • A) Temperature
    • B) Pressure
    • C) Volume
    • D) Concentration
  22. What is the role of entropy change (ΔS) in determining CST?
    • A) It has no role
    • B) It determines the pressure
    • C) It influences the temperature
    • D) It influences the volume
  23. What is the relationship between CST and Gibbs free energy change (ΔG)?
    • A) ΔG is always positive at CST
    • B) ΔG is always negative at CST
    • C) ΔG is zero at CST
    • D) ΔG is infinite at CST
  24. What is the effect of pressure on CST?
    • A) It remains constant
    • B) It decreases with pressure
    • C) It increases with pressure
    • D) It varies with pressure
  25. Which of the following is true about LCST?
    • A) It is the highest temperature at which phase separation occurs
    • B) It is the lowest temperature at which phase separation occurs
    • C) It is the temperature at which a solid melts
    • D) It is the temperature at which a gas liquefies
  26. What is the significance of the phenol-water system in CST studies?
    • A) It is a common example used to study CST
    • B) It is used to measure drug potency
    • C) It is used to assess drug stability
    • D) It is used to determine melting points
  27. What does the term ‘immiscible’ mean?
    • A) Capable of being mixed
    • B) Incapable of being mixed
    • C) Capable of being dissolved
    • D) Incapable of being dissolved
  28. What is the primary factor influencing the distribution ratio?
    • A) Temperature
    • B) Pressure
    • C) Volume
    • D) Concentration
  29. What is the role of CST in creating stable emulsions?
    • A) It determines the melting point
    • B) It ensures complete miscibility
    • C) It measures drug potency
    • D) It assesses drug stability
  30. Which of the following best describes the distribution law?
    • A) It applies to miscible liquids
    • B) It applies to immiscible liquids
    • C) It applies to solids
    • D) It applies to gases

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